The ERG contains an indexed list of hazardous materials and their associated ID numbers, general hazards they pose, and recommended safety precautions.

The 2024 Emergency Response Guidebook provides first responders with a manual intended for use during the initial phase of a transportation incident involving hazardous materials/dangerous goods.

DOT's goal is to place an ERG in every public emergency service vehicle nationwide. To date, more than 18 million free copies have been distributed to the emergency response community through state emergency management coordinators. Members of the public may purchase a copy of the ERG through the GPO Bookstore and other commercial suppliers.

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